Wetenschappelijke publicaties

Category "Genetic psychiatry"

Genome-wide association study of panic disorder reveals genetic overlap with neuroticism and depression Forstner 2021
Dual methylation and hydroxymethylation study of alcohol use disorder Clark 2021
Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders Blokland 2021
Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders Andlauer, TFM April 2021
The association of changes in repetitive negative thinking with changes in depression and anxiety Hijne 2020
Genetic comorbidity between major depression and cardio-metabolic traits, stratified by age at onset of major depression Hagenaars 2020
A methylation study of long-term depression risk Clark 2020
Association of polygenic score for major depression with response to lithium in patients with bipolar disorder Amare 2020
Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank. Coleman JRI 2020
Shared genetic risk between eating disorder- and substance-use-related phenotypes: Evidence from genome-wide association studies. Munn-Chernoff MA 2020
Classical human leukocyte antigen alleles and C4 haplotypes are not significantly associated with depression. Glanville KP 2020
Genome-wide association study of panic disorder reveals genetic overlap with neuroticism and depression. Forstner AJ 2019
Cell type-specific methylome-wide association studies implicate neurotrophin and innate immune signaling in Major Depressive Disorder. Chan RF 2020
A methylation study of long-term depression risk. Clark SL 2019
New alcohol-related genes suggest shared genetic mechanisms with neuropsychiatric disorders. Evangelou E 2019
Involvement of inflammatory gene expression pathways in depressed patients with hyperphagia de Kluiver H 2019
Genome-wide burden of rare short deletions is enriched in Major Depressive Disorder in four cohorts. Zhang X 2019
GWAS of suicide attempt in psychiatric disorders and association with major depression polygenic risk scores Mullins N 2019
Multi-ancestry Genome-Wide Association study of lipid levels incorporating gene-alcohol interactions de Vries PS 2019
Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids. Bentley AR 2019
Long-term glucocorticoid levels measured in hair in patients with depressive and anxiety disorders Gerritsen L 2019
A Potential Role for the STXBP5-AS1 Gene in Adult ADHD Symptoms Arias-Vásquez A 2019
Convergence of evidence from a methylome-wide CpG-SNP association study and GWAS of major depressive disorder Aberg KA 2018
Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders Walters RK 2018
Methylome-wide association findings for major depressive disorder overlap in blood and brain and replicate in independent brain samples Aberg KA 2018
Can chronotype function as predictor of a persistent course of depressive and anxiety disorder? Druiven SJM 2019
Epigenetic aging in Major Depressive Disorder Han LKM 2018
Analysis of shared heritability in common disorders of the brain. Brainstorm Consortium 2018
Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression. Wray NR 2018
Genome-wide regional heritability mapping identifies a locus within the TOX2 gene associated With Major Depressive Disorder. Zeng Y 2017
Huntingtin gene repeat size variations affect risk of lifetime depression Gardiner SL 2017
Leptin dysregulation is specifically associated with major depression with atypical features: evidence for a mechanism connecting obesity and depression. Milaneschi 2017
Does childhood trauma moderate polygenic risk for depression? A meta-analysis of 5765 subjects from the Psychiatric Genomics Consortium. Peyrot WJ 2018
Genome-wide gene-environment interaction in depression: A systematic evaluation of candidate genes: The childhood trauma working-group of PGC-MDD van der Auwera 2018
Genetic association of major depression with atypical features and obesity-related immunometabolic dysregulations. Milaneschi Y 2017
Genome-wide significance for PCLO as a gene for Major Depressive Disorder Mbarek H 2017
HPA axis genes, and their interaction with childhood maltreatment, are related to cortisol levels and stress-related phenotypes. Gerritsen L 2017
Interaction between the FTO gene, body mass index and depression: meta-analysis of 13701 individuals Rivera M 2017
Large normal-range TBP and ATXN7 CAG repeat lengths are associated with increased lifetime risk of depression Gardiner SL 2017
Genome-wide association study of borderline personality disorder reveals genetic overlap with bipolar disorder, major depression and schizophrenia. Witt SH 2017
Clinical phenotypes of perinatal depression and time of symptom onset: analysis of data from an international consortium. Putnam KT 2017
Collaborative meta-analysis finds no evidence of a strong interaction between stress and 5-HTTLPR genotype contributing to the development of depression. Culverhouse RC 2018
Genetic effects influencing risk for major depressive disorder in China and Europe Bigdeli TB 2017
The association of childhood maltreatment with depression and anxiety is not moderated by the oxytocin receptor gene. Tollenaar MS 2017
KLB is associated with alcohol drinking, and its gene product β-Klotho is necessary for FGF21 regulation of alcohol preference Schumann G 2016
An analysis of two genome-wide association meta-analyses identifies a new locus for broad depression phenotype. Direk N 2016
Conditional eQTL Analysis Reveals Allelic Heterogeneity of Gene Expression Jansen R 2017
Exploring boundaries for the genetic consequences of assortative mating for psychiatric traits Wouter PJ 2016
Using clinical characteristics to identify which patients with Major Depressive Disorder have a higher genetic load for three psychiatric disorders Verduijn J 2017
Genome-wide Association for Major Depression through age at onset stratification: Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium. Power RA 2017
Genetic variants in RBFOX3 are associated with sleep latency Amin N 2016
Association of CRTC1 polymorphisms with obesity markers in subjects from the general population with lifetime depression Quteineh L 2016
Genetic relationship between schizophrenia and nicotine dependence Chen J 2016
Pleiotropy between neuroticism and physical and mental health: findings from 108 038 men and women in UK Biobank. Gale CR 2016
Meta-analysis of genome-wide association studies of anxiety disorders. Otowa T 2016
Differential gene expression patterns in smokers and non-smokers: cause or consequence? Vink JM 2016
Genome-wide meta-analysis of cotinine levels in cigarette smokers identifies locus at 4q13.2. Ware JJ 2016
Does refining the phenotype improve replication rates? A review and replication of candidate gene studies on Major Depressive Disorder and Chronic Major Depressive Disorder. Luo X 2016
Meta-analysis of genome-wide association studies for extraversion: findings from the Genetics of Personality Consortium. van den Berg SM 2015
Polygenic dissection of major depression clinical heterogeneity. Milaneschi Y 2016
The genetics of alcohol dependence: Twin and SNP-based heritability, and genome-wide association study based on AUDIT scores. Mbarek H 2015
A common polymorphism in the ABCB1 gene is associated with side effects of PGP-dependent antidepressants in a large naturalistic Dutch cohort. Bet PM 2016
Gene expression in major depressive disorder Jansen R 2016
Meta-analysis of Genome-wide association studies for neuroticism, and the polygenic association with major depressive disorder. Genetics of Personality Consortium 2016
Distinct loci in the CHRNA5/CHRNA3/CHRNB4 gene cluster are associated with onset of regular smoking Stephens SH 2013
ABCB1 gene variants influence tolerance to selective serotonin reuptake inhibitors in a large sample of Dutch cases with major depressive disorder. de Klerk OL 2013
Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. Cross-Disorder Group of the Psychiatric Genomics Consortium 2013
Genome-wide meta-analysis identifies new susceptibility loci for migraine. Anttila V 2013
Refining genome-wide linkage intervals using a meta-analysis of genome-wide association studies identifies loci influencing personality dimensions. Amin N 2013
A K(ATP) channel gene effect on sleep duration: from genome-wide association studies to function in Drosophila. Allebrandt KV 2013
Association between autozygosity and major depression: stratification due to religious assortment. Abdellaoui A 2013
Identification of common variants associated with human hippocampal and intracranial volumes Stein JL 2012
Longevity candidate genes and their association with personality traits in the elderly. Luciano M 2012
Estimating the genetic variance of major depressive disorder due to all single nucleotide polymorphisms. Lubke GH 2012
Multi-locus genome-wide association analysis supports the role of glutamatergic synaptic transmission in the etiology of major depressive disorder Lee PH 2012
Increased genetic vulnerability to smoking at CHRNA5 in early-onset smokers. Hartz SM 2012
Meta-analysis of genome-wide association studies for personality. de Moor M 2012
Genome-wide association and genetic functional studies identify autism susceptibility candidate 2 gene (AUTS2) in the regulation of alcohol consumption Schumann G 2011
A 3p26-3p25 genetic linkage finding for DSM-IV Major Depression in heavy smoking families. Pergadia ML 2011
Genetic risk profiles for depression and anxiety in adult and elderly cohorts. Demirkan A 2011
Replication of association of 3p21.1 with susceptibility to bipolar disorder but not major depression. Breen G 2011
Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior. Thorgeirsson TE 2010
Genome-wide association study of suicide attempts in mood disorder patients. Perlis RH 2010
A genomewide association study of nicotine and alcohol dependence in Australian and Dutch populations. Lind PA 2010
Identifying genetic variants for heart rate variability in the acetylcholine pathway. Riese H 2014
Effect of polygenic risk scores on depression in childhood trauma Peyrot WJ 2014
Further confirmation of the association between anxiety and CTNND2: replication in humans. Nivard MG 2014
Genome-wide analyses of borderline personality features. Lubke GH 2014
Genetic risk score analysis indicates migraine with and without comorbid depression are genetically different disorders. Ligthart L 2014
Role of nicotine dependence in the association between the dopamine receptor gene DRD3 and major depressive disorder. Korhonen T 2014
Applying polygenic risk scores to postpartum depression. Byrne EM 2014
Mineralocorticoid receptor haplotypes sex-dependently moderate depression susceptibilty following childhood maltreatment. Vinkers C 2015
The association between lower educational attainment and depression owing to shared genetic effects? Results in ~25 000 subjects. Peyrot WJ 2015
Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways. The Network and Pathway Analysis Subgroup of the Psychiatric Genomics Consortium 2015
Glucocorticoid and mineralocorticoid receptor polymorphisms and recurrence of major depressive disorder. Hardeveld F 2015
Interaction of neuropeptide Y genotype and childhood emotional maltreatment on brain activity during emotional processing Opmeer EM 2014
A genome-wide association study of depressive symptoms Hek K 2013
A mega-analysis of genome-wide association studies for major depressive disorder Major Depressive Disorder Working Group of the Psychiatric GWAS Consortium 2013
Strong effects of environmental factors on prevalence and course of major depressive disorder are not moderated by 5-HTTLPR polymorphisms in a large Dutch sample Peyrot WJ 2013
Resequencing of three candidate genes for major depressive disorder in a Dutch cohort Verbeek EC 2013
Modulatory effects of the piccolo genotype on emotional memory in health and depression Woudstra S 2013
BDNF val66met affects hippocampal volume and memory related hippocampal activity Molendijk ML 2012
Different gene sets contribute to different symptom dimensions of depression and anxiety van Veen T 2012
A Fine-Mapping Study of 7 Top Scoring Genes from a GWAS for Major Depressive Disorder. Verbeek EC 2012
Piccolo genotype modulates neural correlates of emotion processing but not executive functioning Woudstra S 2012
Genome-wide association study of major depressive disorder: New results, meta-analysis, and lessons learned Wray NR 2012
Poor replication of candidate genes for major depressive disorder using a genome-wide association data Bosker FJ 2011
Common functional mineralocorticoid receptor polymorphisms modulate the cortisol awakening response: interaction with SSRIs Klok MD 2011
A common and functional mineralocorticoid receptor haplotype enhances optimism and protects against depression in females Klok MD 2011
Meta-analysis of genome-wide association for migraine in six population-based European cohorts Ligthart L 2011
Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder Liu Y 2011
The genetic association between personality and major depression or bipolar disorder. A polygenic score analysis using genomewide association data Middeldorp CM 2011
The shared genetics of migraine and anxious depression Ligthart L 2010
Genome-wide association for Major Depressive Disorder: a possible role for the protein PCLO. Sullivan P 2009
Role of gene-stress interactions in gene finding studies. Snieder H 2008
Genome-wide association of major depression: description of samples for the GAIN Major Depressive Disorder Study: NTR and NESDA biobank projects. Boomsma DI 2008