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Introduction

Depression and anxiety disorders are common at all ages. Approximately one out of three people in the Netherlands will be faced with them at some time during their lives. It is still not clear why some people recover quickly and why others suffer for long periods of time. The Netherlands Study of Depression and Anxiety (NESDA) started in august 2004 with the recruitment of almost 3000 people with and without symptoms. They will be monitored for a period of 8 years. An inventory of the depression and anxiety symptoms will be made by using questionnaires and by examining biological and genetic factors. The ZonMw GeestKracht program is subsidizing the study.

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Aim of NESDA

The main aim of NESDA is to determine the factors that influence the development and the long-term prognosis of anxiety and depression. The researchers will try to find answers to important questions like:
- What makes people susceptible to anxiety disorders or depressions?
- Why is one person depressed for three months, while the other is depressed for three years?
- What is the influence of biological and genetic factors?
- What are the implications of a depression or anxiety disorder for income and work?

We expect the results of this study to contribute to the improvement of care for persons with anxiety or depression. In addition, reliable data is needed to establish appropriate preventative measures.

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