Publications 2012

Atlantis E, Vogelzangs N, Cashman K, Penninx BW. Common mental disorders associated with 2-year diabetes incidence: the Netherlands Study of Depression and Anxiety (NESDA). Journal of Affective Disorders 2012; 142 Suppl:S30-S35.

Barakat A, Vogelzangs N, Licht CMM, Geenen R, Macfarlane GJ, de Geus EJC et al. Dysregulation of the autonomic nervous system and its association with the presence and intensity of chronic widespread pain. Arthritis Care Res (Hoboken ) 2012; 64(8):1209-1216.

Bis JC, DeCarli C, Smith AV, van der Lijn F, Crivello F, Fornage M et al. (including NESDA researchers) Common variants at 12q14 and 12q24 are associated with hippocampal volume. Nature Genetics 2012; 44(5):545-551.

Boraska V, at al. (including Penninx BW from NESDA/NTR group). Genome-wide meta-analyses of common variant differences between men and women. Human Molecular Genetetics 2012; 21(21):4805-4815.

Boschloo L, Vogelzangs N, Smit JH, van den Brink W, Beekman AT, Penninx BW. Alcohol dependence, and not alcohol abuse, predicts a poor course of depressive and/or anxiety disorders. British Journal of Psychiatry 2012; 200:476-84.

Boschloo L, Vogelzangs N, van den Brink W, Smit JH, Beekman ATF and Penninx BWJH. Predictors of the 2-year recurrence and persistence of alcohol dependence. Addiction 107: 1639-1640, 2012.

Dastani Z, Hivert MF, Timpson N, Perry JRB, Yuan X, Scott RA et al.
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genetics 2012; 8(3):e1002607.

Eikelenboom M, Smit JH, Beekman AT, Penninx BW. Do depression and anxiety disorders converge or diverge on suicidality? Journal of Psychiatry Research 2012; 46(5):608-15.

Fox CS, Liu Y, White CC, Feitosa M, Smith AV, Heard-Costa N et al. Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women. PLoS Genetics 2012; 8(5):e1002695.

Gerrits M, Vogelzangs N, van Oppen P, van Marwijk H, van Horst H, Penninx BW. Impact of pain on the course of depressive and anxiety disorders. Pain 2012; 153(2):429-36.

Giltay EJ, Enter D, Zitman FG, Penninx BW, van Pelt J, Gooren LJG, Spinhoven P, Roelofs K. Salivary testosterone, depressive and anxiety disorders, and antidepressant use: results from a large cohort study. Journal of Psychosomatic Research 2012; 72(3):205-13.

Glashouwer K, de Jong P, Penninx B. Prognostic value of implicit and explicit self-associations for the course of depressive and anxiety disorders. Behav Res Ther 2012; 50(7-8):479-486.

van der Harst P, et al (including NESDA). Seventy-five genetic loci influencing the human red blood cell. Nature 492: 369-375, 2012.

Hartz, SM, et al (including NESDA). Increased genetic vulnerability to smoking at CHRNA5 in early-onset smokers. Archives of General Psychiatry 2012; 69(8):854-860.

Holleman M, Vreeburg SA, Dekker JJM, Penninx BW. The relationships of working conditions, recent stressors and childhood trauma with salivary cortisol levels. Psychoneuroendocrinology (PNEC) 2012; 37(6):801-9.

Holvast F, Verhaak PFM, Dekker JH, de Waal MW, van Marwijk HW, Penninx BW, Comijs H. Determinants of receiving mental health care for depression in older adults. Journal of Affective Disorders 2012;143:69-74.

Hovens JGFM, Giltay EJ, Wiersma JE, Spinhoven P, Penninx BWJH, Zitman FG. Impact of childhood life events and trauma on the course of depressive and anxiety disorders. Acta Psychiatrica Scandinavica 2012; 126(3):198-207.

Jamal M, van der Does AJW, Cuijpers P, Penninx BWJH. Association of smoking and nicotine dependence with severity and course of symptoms in patients with depressive or anxiety disorder. Drug and Alcohol Dependence 2012; 126(1-2):138-146.

Janssen EHC, van de Ven PM, Terluin B, Verhaak PFM, van Marwijk HWJ, Smolders M, van der Meer K, Penninx BW, van Hout HP. Recognition of anxiety disorders by family physicians after rigorous medical record case extraction: Results of the Netherlands Study of Depression and Anxiety. General Hospital Psychiatry 2012; 34(5):460-467.

Karsten J, Penninx BWJH, Riese H, Ormel J, Nolen WA, Hartman CA. The state effect of depressive and anxiety disorders on the Big Five personality traits. Journal of Psychiatry Research 2012; 46(5):644-50.

Klein Hofmeijer-Sevink M, Batelaan NM, van Megen HJGM, Penninx BW, Cath DC, van den Hout MA, van Balkom AJLM. Comorbidity in anxiety disorder: does it matter? Journal of Affective Disorders 2012; 137(1-3):106-12.

Korten N, Lamers, F, Comijs H, Penninx BW. Late-onset versus early-onset depression. Journal of Affective Disorders 2012; 138(3):259-67.

Lamers F, Hoogendoorn A, Smit J, van Dyck R, Zitman F, Nolen WA, Penninx BW. Socio-demographic and psychiatric determinants of attrition in the Netherlands Study of Depression and Anxiety (NESDA). Comprehensive Psychiatry 2012; 53:63-70.

Lamers F, Rhebergen D, Merikengas K, de Jonge P, Beekman AT, Penninx BW. Stability and transitions of depressive subtypes over a 2-year follow-up. Psychological Medicine 2012, 42(10):2083-93.

Lee PH, Perlis RH, Jung JY et al. (incl. NESDA) Multi-locus genome-wide association analysis supports the role of glutamatergic synaptic transmission in the etiology of major depressive disorder. Translational Psychiatry 2012;2:e184.

Licht CMM, Penninx BWJH and de Geus EJC. Effects of antidepressants, but not psychopathology, on cardiac sympathetic control: a longitudinal study. Neuropsychopharmacology 2012; 37: 2487-2495.

Lubke GH, Hottenga JJ, Walters R, Laurin C, de Geus EJC, Willemsen G, Smit JH, Middeldorp CM, Penninx BWJH, Vink JM, Boomsma DI. Estimating the genetic variance of major depressive disorder due to all single nucleotide polymorphisms. Biological Psychiatry 2012; 72(8):707-709.

Luciano M, et al. (incl. NESDA/NTR: Penninx, Spinhoven, Hartman, Boomsma, de Moor). Longevity candidate genes and their association with personality traits in the elderly. American Journal of Medical Genetics B Neuropsychiatric Genetics 2012; 159B(2):192-200.

Manning A, Hivert M, Scott R, Grimsby J, Bouatia-Naji N, Chen H et al(including NESDA/NTR). A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance. Nature Genetics 2012; 44(6):659-669.

Manthey L, Lohbeck M, Giltay EJ, van Veen T, Zitman FG, Penninx BW. Correlates of benzodiazepine dependence: the Netherlands Study of Depression and Anxiety (NESDA). Addiction 2012; 107(12):2173-82.

van Milligen BA, Vogelzangs N, Smit JH, Penninx BW. Physical function as predictor for the persistence of depressive and/or anxiety disorders. Journal of Affective Disorders 2012; 136(3):828-32.

Molendijk ML, van Tol MJ, Penninx BW, van der Wee NJ, Aleman A, Veltman DJ, Spinhoven P, Elzinga BM. BDNF val66met affects hippocampal volume and memory related hippocampal activity. Translational Psychiatry 2012; 2:e74.

Molendijk ML, Haffmans JPM, Bus BAA et al. Serum BDNF concentrations show strong seasonal variation and correlations with the amount of ambient sunlight. PLoS One. 2012;7:e48046.

Molendijk ML, Bus BAA, Spinhoven P, Penninx BWJH, Prickaerts J, Voshaar RCO and Elzinga BM. Gender specific associations of serum levels of brain-derived neurotrophic factor in anxiety. World journal of biological psychiatry 2012; 13: 535-543.

de Moor MHM, Costa PT, Terracciano A, Krueger R, de Geus EJC, Toshiko T, Hartman C, Esko T, Madden PAF, Derringer J, Amin N, Willemsen G, Hottenga JJ, Distel MA, Uda M, Sanna S, Ferrucci L, Schlessinger D, McCrae RR, Spinhoven P, Penninx BWJH, Realo A, Metspalu A, Heath AC, Pergadia ML, Peng Lin AA, Grucza R, Räikkönen K, Widen E, Luciano M, Tenesa A, Houlihan LM, Davies G, Hansell NK, Medland SE, Wray NR, Wright MR, Aulchenko Y, Janssens ACJW, Oostra BA, Allik J, Abecasis GR, Deary IJ, Bierut L, Martin NG, Boomsma DI, van Duijn CM. Meta-analytic genome-wide association study in >17.000 individuals reveals new loci for the Five-Factor Model (NEO-FFI) personality domains. Molecular Psychiatry 2012; 17(3):337-49.

Murabito JM, et al. (incl. NESDA: Penninx, Seldenrijk, Snieder). Association between chromosome 9p21 variants and the ankle-brachial index identified by a meta-analysis of 21 genome-wide association studies. Circulation. Cardiovascular Genetics 2012; 1;5(1):100-12.

Okada Y, et al. (including NESDA). Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations. Nature Genetics 2012; 44: 904-909.

Palmer ND, at al. (incl NESDA/NTR, MAGIC: Penninx, Vogelzangs, Boomsma, de Geus, Hottenga, Willemsen). A genome wide association search for type 2 diabetes genes in African Americans. PLOS One 2012; 7(1): e29202.

Piek E, Nolen WA, van der Meer K, Joling KJ, Kollen BJ, Penninx BW, van Marwijk HW, van Hout HP. Determinants of recognition of depression by general practitioners: results of the Netherlands Study of Depression and Anxiety. Journal of Affective Disorders 2012; 138(3):387-404.

Piek E, van der Meer K, Hoogendijk WJ, Penninx BW, Nolen WA. Weinig overbehandeling met antidepressiva. Huisarts en Wetenschap 2012;55(2):54-57.

Plaisier I, de Graaf R, de Bruijn J, Smit J, van Dyck R, Beekman A and Penninx B. Depressive and anxiety disorders on-the-job: the importance of job characteristics for good work functioning in persons with depressive and anxiety disorders. Psychiatry Research 2012; 20: 382-388.

van Reedt-Dortland A, Giltay E, van Veen T, Penninx BW, Zitman FG. Personality traits and childhood trauma as correlates of metabolic risk factors: The Netherlands Study of Depression and Anxiety (NESDA). Progress in Neuropsychopharmacology & Biological Psychiatry 2012; 36(1):85-91.

Rhebergen D, Lamers F, Spijker J, de Graaf R, Beekman ATF, Penninx BWJH. Course trajectories of unipolar depressive disorders identified by latent class growth analysis. Psychological Medicine 2012; 42(7):1383-1396.

Seekles W, Cuijpers P, van der Ven P, Penninx BW, Verhaak P, Beekman A, van Marwijk H, van Straten A. Perceived need for mental health care and personality among primary care patients. Journal of Affective Disorders 2012; 136(3):666-74.

Scott RA et al (MAGIC consortium, including NESDA). Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways. Nature Genetics 2012; 44(9):991-1005.

Spinhoven P, de Rooij M, Heiser W, Smit J, Penninx BWJH. Personality and changes in comorbidity patterns among anxiety and depressive disorders. Journal of Abnormal Psychology 2012 ;121(4):874-84.

Stein JL, Medland SE, Vasquez AA, Hibar DP, Senstad RE, Winkler AM et al. Identification of common variants associated with human hippocampal and intracranial volumes. Nature Genetics 2012; 44(5):552-61.

Stoffers D, Moens S, Benjamins J, van Tol MJ, Penninx BWJH, Veltman DJ, van der Wee NJA and Van Someren EJW. Orbitofrontal gray matter relates to early morning awakening: a neural correlate of insomnia complaints? Frontiers in Neurolology 2012; 3: 105.

van Tol MJ*, Demenescu LR*, van der Wee NJ, Kortekaas R, den Boer JA, Renken R, van Buchem MA, Zitman FG, Aleman A, Veltman DJ. fMRI correlates of emotional word encoding and recognition in depression and anxiety disorders. Biological Psychiatry 2012; 17(7):593-602. *shared first authorship

van Veen T, Goeman JJ, Monajemi R, Wardenaar KJ, Hartman CA, Snieder H et al. Different gene sets contribute to different symptom dimensions of depression and anxiety. American Journal of Medical Genetics B Neuropsychiatric Genetics 2012; 159(5):519-528.

Veen G, Giltay EJ, Vreeburg SA, Licht CM, Cobbaert CM, Zitman FG et al. Determinants of salivary evening alpha-amylase in a large sample free of psychopathology. International journal of psychophysiology 2012; 84(1):33-38. Nederlandse samenvatting.

Verbeek EC, Bakker IMC, Bevova MR, Bochdanovits Z, Rizzu P, Sondervan D et al. A Fine-Mapping Study of 7 Top Scoring Genes from a GWAS for Major Depressive Disorder. PLoS One 2012; 7(5):e37384.

Verboom CE, Ormel J, Nolen WA, Penninx BWJH, Sijtsema JJ. Moderators of the synchrony of change between decreasing depression severity and disability. Acta Psychiatrica Scandinavica 2012; 126(3):175-185.

Vogelzangs N, Duivis HE, Beekman AT, Kluft C, Neuteboom J, Hoogendijk W, Smit JH, de Jonge P, Penninx BW. Association of depressive disorders, depression characteristics and antidepressant medication with inflammation. Translational Psychiatry 2012; 2: e79.

Wardenaar KJ, Giltay EJ, van Veen T, Zitman FG, Penninx BW. Symptom dimensions as predictors of the two-year course of depressive and anxiety disorders. Journal of Affective Disorders 2012; 136(3):1198-203.

Wardenaar KJ, Giltay EJ, van Veen T, Zitman FG, Penninx BWJH. Dimensions of the Inventory of Depressive Symptomatology as predictors of the course of depressive and anxiety disorders. Journal of Psychiatric Research 2012;46:1655-1661.

Woudstra S, Bochdanovits Z, van Tol MJ, Veltman DJ, Zitman FG, van Buchem MA, van der Wee NJ, Opmeer EM, Demenescu RL, Aleman A, Penninx BW, Hoogendijk WJ. Piccolo genotype modulates neural correlates of emotion processing but not executive functioning. Translational Psychiatry 2012 (2):e99.

Wray NR, Pergadia ML, Blackwood DHR, Penninx BWJH, Gordon SD, Nyholt DR, Ripke S, MacIntyre DJ, McGhee KA, Maclean BS, Smit JH, Hottenga JJ, Willemsen G, Middeldorp C, de Geus EJ, Lewis CM, McGuffin P, Hickie IB, van den Oord EJ, Liu JZ, Macgregor S, McEvoy BP, Byrne EM, Medland SE, Statham DJ, Henders AK, Heath AC, Montgomery GW, Martin NG, Boomsma DI, Madden PAF, Sullivan PF. Genome-wide association study of major depressive disorder: New results, meta-analysis, and lessons learned. Molecular Psychiatry 2012; 17:38-48.

Yang J, et al (incl. NESDA/NTR). FTO genotype is associated with phenotypic variability of body mass index. Nature 2012; 490(7419):267-272.